/\ Dude, go for a custom MS install if you're familiar with it already:
http://www.aaroncake.net/RX-7/megasq...asicTuning.asp
It will be much cleaner and get rid of a lot of shit like the MAF, variable resistor, etc etc etc, replace all that 20yo crusty ass wiring, and just generally be better than a plug n play.
You could go with an RTEK 2.0 ecu upgrade, but that is like $400 already, plus extra for PDA and cable, and I would recommend a fresh factory harness with that setup anyway (cork-sport: $800)
You can use the S5 stuff but you will need to use all S4 sensors n shit with the stock ECU. To run an S4 omp, you will need to use the S4 front cover. The S5 engine uses the emissions air pump to activate the 6pt system and the VDI system. I would take out the sleeves completely and not worry about it. After a certain point (this was told to me by Chris Ludwig, professional tuner) the sleeves do more bad than good. (high rpm airflow restriction) same with VDI...
If you can, keep the middle intake manifold S4, or weld open the vdi thing...
Here's my suggestion:
Tear apart both S4 and S5 blocks, and use the best parts out of both. IE: Spec the irons and check the housings for wear, use ones with least wear.
Use S5 rotors, front counterweight, and flywheel. Use an S4 front cover. If you go with a 6pt turbo however, you could run the slightly lower comp S4 rotors. The S5 N/A rotors are the highest comp 13B rotors, people use them in 300hp 3 rotor N/A builds.
Buy a racing beat main pulley. (s4 and s5 engines had different timing marks on the pulleys, if you screw up which ones went on where, you wont be able to time the engine very well. The RB pulley is make differently and has TDC mark)
Use S5 upper manifold with S4 throttle body.
Stock injectors on n/a are like 400cc and can support up to 200hp, they will be fine. Get a fresh pump( walbro stock replacement or 255lph if you go turbo, new fuel filter, and get the injectors refurbished (around $80 for 4 injectors)
EDIT: get a mild steet port if you want. You CAN send the engine to Kevin Landers and have it rebuilt
and ported for around $1600. Considering he's a professional, and a rebuild kit already costs $950 This is a hell of a deal.
And I didn't even mention that most places charge about $3000 for a rebuilt motor.