The Rtek should be able to handle your goal with minimal issue. especially if you use the injector presets available within the software. For instance you can select 550/720 and it will automatically adjust the fuel to run on those injectors and achieve the stock flow, which will let you get your 3 hour road trip without issue. Tuning on the other hand is slow. you have little direct input (ie writing in the number) and must use the sliders. Beyond that data logging and other functions are easy to use. On the other hand I do not know when the built in fuel cut will start nor the max load reading on the RTek is, which may limit your HP goal, but i doubt it will be an issue.
If you were doing an NA build I'd sell you mine