Twins would give you the ultimate set-up, but getting the sizing right + increased cost / labor due to all the custom work might not be possible for you?
If you do have the resources to go individual twins, I wholeheartedly agree with that choice...
But since the title says just "turbo"...
My philosophy with turbo sizing is to always run as big of a turbo you can afford which will spool decently and keep the boost down.
You can run smaller turbos for better spool, but you end up jacking the boost up to compensate.
I'd rather keep the boost lower and run the larger sized turbo and just size down the turbine A/R if really needed.
For single turbo set-up's, I will not go anything smaller than a GT3582,
I set up a recent customer with an HKS cast collected turbo exhaust manifold, 60-1 / O-trim / 0.96 A/R turbine, Tial 44mm wastegate that had full spool by 3,800RPM.
Not the most responsive, but it does give us a baseline.
Yeah, the O-trim is considered small, but we were pleasantly surprised it ran a flat torque line all the way to 7kRPM at 12psi.
The numbers were 280 @ 12psi, 300 @ 15psi, 320 @ 18psi on a Dynapack, so this turbo will hit a true 350 @ the wheels at the edge of pump gas on a DynoJet.
Now, let's look into the spool portion of this set-up...
The HKS cast, collected turbo exhaust manifold is probably the worst flowing out of all the options out there.
Almost any tube turbo exhaust manifold will flow better, which means better spool.
Going with a more efficient flowing tube turbo exhaust manifold should drop the full boost spool down to 3,500RPM (or lower) easily.
Going with a full, divided set-up - i.e. keep front rotor versus rear rotor exhaust pulses separated through all the way to the turbine housing (divided turbine housing, twin wastegates, etc.) - and you're looking at low 3,000RPM...3,300RPM...3,200RPM full spool.